Download Cell Death During HIV Infection by Andrew D. Badley PDF
By Andrew D. Badley
So as to transcend immune-based cures, researchers at the moment are contemplating the consequences of apoptosis dysregulation in the course of HIV-induced immunodeficiency. This paintings presents the 1st complete compendium of the growth made in figuring out the method of telephone loss of life regarding HIV and the capability breakthroughs in remedy that supply a lot promise. Combining the paintings of greater than two-dozen best researchers, this seminal quantity presents clinicians and researchers with a very good reference, whereas additionally serving as an incubator to stimulate destiny learn. It explains the basic biology concerned with apoptosis, explains its scientific impression in HIV, and examines the latest healing techniques.
Read Online or Download Cell Death During HIV Infection PDF
Best infectious diseases books
Aegean meetings is an self reliant, nonprofit, academic association directed and controlled by way of the medical group. The board is made of 9 researchers/scientists in numerous disciplines from Harvard, Brown, collage of Pennsylvania, UCSD, Princeton, Biovista and the root for Biomedical study Academy of Athens.
Lieber EXPERIMENTATOR,seit der Erstauflage im Jahr 2004 ist nun die four. Auflage des Immuno-EXPERIMENTATORS erschienen. Das Werk präsentiert die methodische Vielfalt der Immunologie, indem es die gängigen Methoden auf einfache Weise erklärt und auf Vor- und Nachteile sowie auf kritische Punkte eingeht.
- Pathology and Pathophysiology of Human Viral Disease
- The Nobel Prize Winning Discoveries in Infectious Diseases
Additional resources for Cell Death During HIV Infection
Craig, B. Mangeat, N. Klages, R. Evans, G. Kalpana, and D. Trono, Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication, Mol. Cell, 7, 1245–1254, 2001. 169. J. D. Bushman, Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid protein, J. , 73, 6670–6679, 1999. 170. , M. J. Wang, S. Perumal, D. V. Kalpana, Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance, J.
158, 1014–1019, 1997. 178. , K. A. S. Singer, Repression of MHC class I gene promoter activity by two-exon Tat of HIV, Science, 260, 1320–1322, 1993. 179. , J. Hauber, R. R. Cullen, Immunodeficiency virus Rev trans-activator modulates the expression of the viral regulatory genes, Nature, 335, 181–183, 1988. 180. W. H. Malim, The HIV-1 Rev protein, Annu. Rev. , 52, 491–532, 1998. 181. , M. Stuchell, B. M. Y. Chung, E. E. Wang, T. P. M. Cimbora, A. G. Krausslich, J. G. I. Sundquist, The protein network of HIV budding, Cell, 114, 701–713, 2003.
Whereas Bok expression seems to be limited to reproductive tissues, Bax and Bak are widely distributed. 12,13 The third subclass comprises the BH3-only members, proapoptotic proteins containing only the BH3 domain. Members of this group are Bid, Bik, Bad, Hrk, Bim, Bmf, Noxa, and Puma. They act as sensors to promote apoptosis in response to proximal death signals or intracellular damage, generally (but not exclusively) by binding to and neutralizing their prosurvival relatives. To prevent unnecessary triggering of apoptosis, in healthy cells, they are subjected to tight regulation either by transcriptional control or posttranslational modification or cellular compartmentalization.