Download Encyclopedia of Medical Immunology: Allergic Diseases by Ian R. Mackay, Noel R. Rose, Dennis K. Ledford, Richard F. PDF

By Ian R. Mackay, Noel R. Rose, Dennis K. Ledford, Richard F. Lockey

Volume Allergic ailments is a accomplished, multi-authored reference paintings, providing a large entice microbiologists, immunologists, and infectious sickness experts. the quantity explores all points of allergic ailments, physique structures and vaccines. Emphasis is put on genetics, body structure, metabolism, pathogenesis, and utilized microbiology. less than the management of a few of the main international well known names within the box, the encyclopedia brings jointly an excellent number of contributions through most sensible scientists in a number of fields.

The entries are indexed alphabetically and supply complete references.

The quantity covers the subsequent topics:

• nutrition allergic reaction and gastrointestinal Allergic Diseases

• Insect Allergy

• hypersensitivity prognosis and Testing

• hypersensitive reaction therapy: Pharmacotherapy

• bronchial asthma and different Allergic reduce breathing Disease

• Biology of IgE, Mast Cells and Eosinophils

• particular Allergens inflicting Human Disease

• Atopic Dermatitis, Urticaria and Dermatologic Allergy

• hypersensitivity therapy: Immunotherapy, Immunomodulator remedy and Allergen Avoidance

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Additional resources for Encyclopedia of Medical Immunology: Allergic Diseases

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Allergic Contact Dermatitis Allergic contact dermatitis (ACD) is a type IV cell-mediated reaction that is usually delayed and involves capture of allergens via dendritic cells at Irritant contact dermatitis (ICD) is mediated through a non-immunologic mechanism with inflammatory reaction. As the mechanism is different from ACD, the symptoms typically start sooner. ICD is usually limited to the areas of contact with the irritant substances and has sharp demarcation (Fonacier et al. 2010). Latex Allergy Natural rubber latex allergy can provoke both IgEmediated symptoms, such as angioedema, urticaria, and anaphylaxis, as well as contact dermatitis.

Blood. 2013;121:2393–401. Huber M. Activation/inhibition of mast cells by supra-optimal antigen concentrations. Cell Commun Signal. 2013;11:7. Hur EM, Kim KT. G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity. Cell Signal. 2002;14:397–405. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O. Signaling through the hematopoietic cytokine receptors. Annu Rev Immunol. 1995;13:369–98. Jonsson F, Dae¨ron M. Mast cells and company. Front Immunol. 2012;3:16.

Altogether, chemokine receptors attract mast cells by stimulating chemotaxis in response to a variety of chemoattractants. By acting on mast cell purinergic receptors, adenosine present in extracellular fluid contributes to asthma symptoms. Adenosine indeed provokes a mast-celldependent bronchoconstriction in asthmatic and chronic obstructive pulmonary disease patients (Rudich et al. 2012). Corticotropin-releasing A 8 hormone receptors are thought to account for stress-induced inflammation and stress-enhanced allergic reactions.

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