Download Diagnostic Neuropathology: Volume II by J. Escalona-Zapata (auth.), Julio H. Garcia M.D., Julio PDF

By J. Escalona-Zapata (auth.), Julio H. Garcia M.D., Julio Escalona-Zapata M.D., Uriel Sandbank M.D., Jorge Cervós-Navarro M.D. (eds.)

Every 12 months dozens of physicians-in-training face, for the 1st time, the responsibil­ ity of analyzing and diagnosing important anxious approach tumors or biopsies of the significant fearful approach, the peripheral nerves or muscle tissues, whose surgical resection has been selected either as a sort of remedy (in the case of tumors) and as capability to substantiate a presumptive analysis. the choice of the main applicable kind of publish surgical procedure for many tumors relies at the special identity of the tumor cells. The evaluate of the specimen, via a pathologist, won't merely verify no matter if the lesion is really neoplastic, but additionally no matter if there are histologic symptoms of malig­ nancy. additionally, often times, the pathologist might be requested to figure out even if the tumor cells include yes hormone precursors or receptors, to illustrate. reputation of the various good points that one needs to look for calls for the really apt software of equipment that won't be effortlessly recognized to the physicians all for a number of the diagnostic systems. The dealing with and processing of the tissues as they come within the pathology laboratory for the above purposes range as a functionality of the organ (or website) of beginning of a given tumor in addition to a functionality of the presumptive medical analysis. the cloth contained during this publication sequence has been geared up in an try and aid the pathologists-in-training, the overall pathologists, the neurosurgeons, and neu­ rologists to appreciate the common sense at the back of such unique requirements.

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5-26 and 5-27). In the late stages there appears in the interior of the mosaic, round eosinophilic epithelial structures, either without nucleus or with a basophilic central round structure. These are the in vitro equivalents of the keratin balls. It is common to find cells with cytoplasmic granules of keratohyaline (eleidin), whose presence can be demonstrated by means of the Astrablau. Craniopharyngioma has been defined by the application Fig. 5-26. Craniopharyngioma after 6 days in culture. Characteristically, the explant shows three concentric layers.

Liss L: Morphology of nervous system tumors in vitro, in Proceedings of the 6th International Congress on Neuropathology, Vol. 2. Stuttgart, G. Thieme, 1962, 247-254. 60. Lumsden CE: The study by tissue culture of tumors of the nervous system, in 3rd Edition E Rus&ellRubinstein, (ed): Pathology of Tumors of the Nervous System, London, E Arnold, 1971. 61. Lumsden CE: Tissue culture of brain tumors, in Vinken-Bruyn: Handbook of Clinical Neurology, Vol. 17/II. North Holland Publ. , Amsterdam, 1974, 42-103.

According to Cravioto and Lockwood, only the fusiform cells and the ameoboid cells are authentically of schwannian derivation. The coexistence of fusiform cells and macrophages has been confirmed experimentally. 32•81 Thust, et al88 interpret the macrophages as being accompanying cells, while Escalona-Zapata and Diez-Nau23•27 believe that these are of Schwann derivation. The pure fusiform cell population of the cases reported by Mennell and Bucheler65 is explained by the high malignancy rate of the drug-induced tumors and is comparable to the observations reported in malignant human schwannomas.

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