Download Cytokines (Handbook of Immunopharmacology) by Anthony R. Mire-Sluis, Robin Thorpe PDF

By Anthony R. Mire-Sluis, Robin Thorpe

This ebook presents accomplished assurance of the cytokines from a pharmacological method. The chapters are provided in a constant structure permitting effortless cross-reference, with pattern diagrams and a precis desk of crucial proof for every bankruptcy on the finish of the book.Cytokines is exclusive in stressing cytokine biology and the applying of study info to supply illness treatment. With 33 specific and updated chapters approximately person cytokines, this finished reference will offer either clinicians and researchers in immunology and pharmacology with important details. Key gains* Genetic details and sequences* Protein constitution* phone resources and creation* organic job* Cytokine receptor constitution and sign transduction* dialogue of the function of cytokines in illness and the potential of treatment* precis desk of crucial proof* complete bibliography

Show description

Read Online or Download Cytokines (Handbook of Immunopharmacology) PDF

Best basic science books

Microorganisms and Bioterrorism

The aim of this e-book is to compile, in one quantity, the main updated info bearing on microbes with strength as bioterrorist guns. the first viewers comprises microbiologists, together with bacteriologists, virologists and mycologists, in academia, govt laboratories and learn institutes on the leading edge of reviews touching on microbes that have strength as bioterrorist guns, public well-being physicians and researchers and scientists who has to be knowledgeable to accommodate bioterrorist assaults in addition to laboratory investigators who needs to establish and symbolize those microorganisms from the surroundings and from in all likelihood contaminated sufferers.

Chromosomal Instability and Aging: Basic Science and Clinical Implications

This article examines the connection among DNA harm and service, mobile senescence, genomic instability and ageing. It contains in-depth discussions of assorted sorts of DNA harm, the DNA fix community, and mobile responses to genetic harm to evaluate their influence at the modulation of growing older approaches and age-related disorder, together with melanoma improvement.

Trichloroethylene: Toxicity and Health Risks

A finished assessment of the consequences of trichloroethylene toxicity because of real-life publicity degrees highlighting how publicity to trichloroethylene might give a contribution to the etiology of a number of idiopathic human illnesses. dialogue will concentrate on other kinds of modeling and the way they're used to foretell useful results and to dissect the contribution of other mechanistic pathways, together with power mechanisms of motion for trichloroethylene toxicity in several organ structures.

Platelet Proteomics: Principles, Analysis, and Applications

The aim of the booklet is to introduce platelets, and their practical function in thrombotic and heart problems, justifying the relevance of platelet proteomics study. concentration then shifts to the hot advancements on mass spectrometry (MS)-based proteomics.  This bankruptcy indicates capability functions for platelet proteomics no longer but performed.

Additional resources for Cytokines (Handbook of Immunopharmacology)

Sample text

Et al. (1986). Complete nucleotide sequence of the gene for human interleukin 1 alpha. Nucleic Acids Res. 14, 3167. Ghezzi, P. A. (1988). IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma. J. Immunol. 140, 4238. , Kumar, S. and Baglioni, C. (1993). Tumor necrosis factor increases stability of interleukin-1 mRNA by activating protein kinase C. J. Biol. Chem. 268, 6214. V. and Pennica, D. (1986). Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta.

1986). Cytotoxicity of human pl 7 interleukin-1 for pancreatic islets of Langerhans. Science 232, 1545. , Rossini, M. and Melli, M. (1990). An inducible enhancer controls the expression of the human interleukin i beta gene. Cell Growth Diff. 1,491. , Bianchi, M. and Ghezzi, P. (1988). Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J. Exp. Med. 167, 1708. S. A. Jr (1984). Interleukin-1 (IL-1) induces biosynthesis and cell surface expression ofprocoagulant activity in human vascular endothelial cells.

Blood 83, 1738. , Mantovani, A. and Colotta, F. (1994b). Induction by transforming growth factor-beta 1 of the interleukin-1 receptor antagonist and of its intraceUular form in human polymorphonuclear cells. Eur. J. Immunol. 24, 3194. , et al. (1995). Cloning and characterization of a new isoform of the interleukin-1 receptor antagonist. J. Exp. Med. 182, 623. J. D. (1988). Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor.

Download PDF sample

Rated 4.75 of 5 – based on 50 votes