Download Cytokines and Cancer by Anupama Gururaj, Rakesh Kumar (auth.), Leonidas C. Platanias PDF

By Anupama Gururaj, Rakesh Kumar (auth.), Leonidas C. Platanias MD, PhD (eds.)

This quantity presents a finished evaluate of the present wisdom on cytokines and melanoma. Cytokines play various roles in melanoma, either as elements of pathogenetic mechanisms, in addition to brokers utilized in the remedy of yes malignancies. so far, there has no longer been a e-book released that covers either simple technological know-how and translational/clinical examine within the box of cytokines in malignancies.

The quantity is split in sections. part one makes a speciality of present advancements within the easy technological know-how box with specific emphasis on novel mechanisms of cytokine activities in malignant cells. the second one part bargains with translational and medical learn within the box, and plenty of of the bankruptcy authors have been one of the first to introduce numerous cytokines within the therapy of sure tumors.

Cytokines and Cancer is written via major figures within the box of cytokine biology and cytokine therapeutics and is in particular serious about this topic.

Collectively, the knowledge supplied during this publication could be invaluable to humans within the scientific box at a number of degrees, together with clinical scholars, interns, citizens, medical and simple technological know-how researchers, in addition to oncologists in practice.

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2499-505. 107. , Regulation of the pro-angiogenic microenvironment by carboxyamido-triazole. J Cell Physiol, 2003. 197(1): p. 139-48. CYTOKTNES AND CANCER 108.

1-18. 2. M. N. Fish, Chemokines: attractive mediators of the immune response. Semin Immunol, 2003. 15(1): p. 5-14. 3. , A chemoattractant expressed in human sarcoma cells (tumor-derived chemotactic factor, TDCF) is identical to monocyte chemoattractant protein-l/monocyte chemotactic and activatingfactor (MCP-I/MCAF). Int J Cancer, 1990. 45(4): p. 795-7. 4. , Regulation of the macrophage content of neoplasms by chemoattractants. Science, 1983. 220(4593): p. 210-2. 5. , Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma.

Signalingpathways involved in the chemotactic activity of CXCLl2 in cultured rat cerebellar neurons and CHPIOO neuroepithelioma cells. J Neuroimmunol, 2003. 135(1-2): p. 38-46. , Expression and function of chemokine receptors in human multiple myeloma. Leukemia, 2003. 17(1): p. 203-10. , Expression of CXCR4 and CXCLIZ (SDF-I) in human prostate cancers (PCa) in vivo. J Cell Biochem, 2003. 89(3): p. 462-73. , Possible role of stromal-cell-derived factor-I/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma.

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