Download Breast Cancer Stem Cells & Therapy Resistance by Phuc Van Pham PDF

By Phuc Van Pham

This quantity completely examines breast melanoma stem cells (BCSCs), from easy definitions to options for settling on, keeping apart, culturing, and focusing on BCSCs for remedy; there's extra concentrate on pre-clinical and medical effects. The textual content starts with a dialogue of breast melanoma, focusing particularly at the obstacles of present treatments in its therapy. the following chapters introduce and examine stem cells and melanoma stem cells, describe houses and isolation options of BCSCs, and look at BCSC-targeting techniques. The textual content concludes with a dialogue of controversy surrounding the BCSC speculation and of destiny study instructions. Breast melanoma Stem Cells & treatment Resistance, a part of the SpringerBriefs in Stem Cells sequence, presents a succinct but complete evaluation of BCSCs for complex scholars, graduate scholars and researchers in addition to these operating with breast melanoma or stem cells in a medical setting.

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C. (2014). ALDH1A1 expression correlates with clinicopathologic features and poor prognosis of breast cancer patients: A systematic review and meta-analysis. BMC Cancer, 14, 444. Liu, T. , Sun, B. , Zhao, X. , Zhao, X. , … Liu, N. (2013). CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancer. Oncogene 32(5), 544–553. , & Rappa, G. (2011). Phenotypic heterogeneity of breast cancer stem cells. Journal of Oncology, 2011, 135039. , & Gianni, A.

Seo, J. H. (2014). Association of aldehyde dehydrogenase 1 expression and biologically aggressive features in breast cancer. Neoplasma, 61(3), 352–362. , … Mori, M. (2013). Cancer stem cells depend on their own niche. Gan To Kagaku Ryoho, 40(4), 419–423. Kleinsmith, L. , & Pierce, G. , Jr. (1964). Multipotentiality of single embryonal carcinoma cells. Cancer Research, 24, 1544–1551. , … Dick, J. E. (1994). A cell initiating human acute myeloid leukaemia after transplantation into SCID mice.

The SP cell phenotype was first discovered in 1996 in mouse bone marrow. SP cells in bone marrow are related to hematopoietic stem cells (Goodell, Brose, Paradis, Conner, & Mulligan, 1996). , 2003) and tumors including breast tumor (Britton, Kirby, Lennard, & Meeson, 2011). In the stem cell analysis, a side population is defined as a minor cell population that exhibits low-intensity staining with dyes such as Hoechst 33342 (H33342) or rhodamine 123 (R123). Both H33342 and R123 easily stain cells because they can cross the cell membrane.

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